Founders Longevity Forum gathered leading experts to explore the most promising and provocative, developments in human longevity.
From biomarkers to biostasis, the Founders Longevity Forum encouraged leading scientists, clinicians, entrepreneurs and investors to chart the future of human health – where innovation meets healthspan expansion and radical life extension. This article offers a strategic, high-level recap of the event through the lens of Longevity 1.0 to 3.0. While not every speaker or session is covered in detail, this overview highlights key themes and takeaways. We encourage attending future events to experience the full breadth, depth and dynamic energy that these gatherings exclusively offer.
Following editions in London in 2024 and Singapore earlier this year, the third iteration of Founders Longevity Forum, continues the partnership between Longevity.Technology and Founders Forum, delivered a unique convergence of scientific insight, entrepreneurship and philosophical reflection. With speakers ranging from biotech CEOs to investors and futurists, the event offered a state-of-the-industry debrief and a glimpse into what the near and distant future of longevity might look like.
Phil Newman (Founder & CEO, Longevity.Technology) opened with a keynote setting the scene. Where aging is the biggest driver of chronic disease, yet 85% of US healthcare expenditure goes to chronic diseases, longevity is not only an exciting and dynamic field but one that has a lot to offer and holds solutions to some of the biggest problems facing humanity today. Introducing his Ten Levels of Longevity, a conceptual map outlining the industry’s trajectory from simple lifestyle interventions to speculative digital immortality, this framework not only defined the day’s discussions, it also helps us map the industry’s present, its near-term evolution and longer-term ambitions.
The Ten Levels of Longevity
| Longevity 1.0 (healthspan) | Level 1: Lifestyle management Level 2: Consumer diagnostics Level 3: Longevity biohacking Level 4: Longevity clinical services |
| Longevity 2.0 (lifespan) | Level 5: Aging disease management Level 6: Aging disease prevention therapeutics Level 7: Targeted aging reversal |
| Longevity 3.0 (escape velocity and beyond) | Level 8: Systemic aging reversal Level 9: Organ/organism preservation Level 10: Corporeal or consciousness preservation |
This piece will discuss the sessions across three thematic lenses: Longevity 1.0 (healthspan), Longevity 2.0 (lifespan) and Longevity 3.0 (escape velocity and beyond).
Longevity 1.0: Lifestyle, diagnostics and biohacking
In the Longevity 1.0 space, much of the discussion centered around data-driven prevention, how emerging tools are helping individuals understand and influence their healthspan earlier and more effectively.
Data and diagnostics
Matthew Dawson (CEO, TruDiagnostic) opened the diagnostics panel by reframing health as a data challenge. With advances in AI and access to large-scale epigenetic datasets, his team is developing blood-based diagnostics that can predict disease risk decades in advance with greater precision than conventional biomarkers. Backed by Illumina, their aim is to move diagnostics upstream, enabling earlier, more targeted interventions.
Michael Geer (Co-founder, Humanity) echoed this idea, highlighting that much of the biological data we need already exists, but we’re using it inefficiently. He proposed the use of open large biological models (akin to LLMs) that can process biological data in temporal and spatial context. He argued that these tools could unlock personalized prevention at scale, particularly as biological age serves as a behavioral catalyst.
In a moderated discussion led by Judith Mueller (Director, Single Family Office), the panel explored how in silico models, simulations run entirely on biological data, may soon rival, or even outperform, traditional in vitro and in vivo trials in predicting therapeutic efficacy and safety. Yet as the field races ahead, standardisation is lagging.
The panel questioned what “biological age” actually means. While many commercial tests benchmark against a notional 21-year-old for example, more rigorous models compare biological aging against disease probability curves, particularly those derived from epigenetic data. The consensus: without validated definitions and robust standards, the clinical utility of “bioage” diagnostics remains limited, and so does their ability to support therapeutic development or personalized healthcare at scale.
Biomimicry and health optimisation
The biohacking session explored the application of non-invasive technologies as synergistic health optimisation tools. Erin Lee (Founder & CEO, Touchless Wellness Association) introduced the concept of “stackable wellness”, a systems-based approach that layers modalities like photobiomodulation, halotherapy and cold exposure. When used with intention and sequencing, these interventions can enhance resilience and recovery. But if poorly combined, they risk introducing negative physiological stress. Her key message: order matters, and diagnostics are essential to personalise protocols according to bio-individuality.
Dr Ash Kapoor (Medical Director, Levitas Group & CEO/COO, Levitas One) deepened the conversation by linking biological and psychological stress to aging. He argued that our cells have evolved for scarcity, yet now exist in abundance, leading to mismatches that accelerate dysfunction. His perspective echoed a recurring thread across the day: the best innovation often mimics nature, with interventions like fasting, heat, cold and breathwork activating ancient cellular pathways of repair and resilience.
Renowned biohacker Tim Gray (Founder & CEO, Health Optimisation Summit) brought the session back to fundamentals. The goal, he reminded us, isn’t immortality, it’s vitality. And the biggest returns still come from reconnecting with the basics: high-quality sleep, light exposure, nutrient-rich food and community.
Finally, Dr Tamsin Lewis (Founder & Medical Director, Wellgevity) offered a softer reframe of the term “biohacking,” proposing “bio-harmonising” – a term more aligned with systems biology and biomimicry, and less suggestive of stress or control. It’s a fitting concept for a field increasingly focused not just on extending life but living in greater alignment with the natural systems that sustain it.
Longevity 2.0: Clinics, services and decelerating aging
Here, the conversation shifted from lifestyle optimization to disease-modifying interventions and early-stage therapeutics with measurable effects on aging biomarkers and disease progression.
This portion of the day opened with perhaps its most thought-provoking and high-profile session: a live Q&A with Bryan Johnson, the tech entrepreneur behind the Blueprint project and a prominent figure in experimental longevity.
Through a candid dialogue with the audience, he discussed everything from HRV as his leading health metric to sexual health, ethics and the corporate drivers of chronic disease. His message was philosophical and provocative, challenging assumptions about health, identity and technology.
When asked if he would have been as successful had he prioritized his health earlier in his career, his response was immediate. “I would’ve made way more money if I had prioritized my health,” he said.
Johnson then laid out his broader vision, arguing that humanity is woefully under-equipped for the era of artificial superintelligence. “We are cave people relative to AI,” he told the audience. “We don’t yet have the mental models to define what it means to be human in this next epoch.”
He described modern society as being built on a paradox, sacrificing our biology for technological progress, despite the fact that we ourselves are the most important product we’ve ever created. His “Don’t Die” philosophy is not about chasing immortality, but about establishing a unifying operating system for health, ethics and planetary stewardship.
“More blood has been shed over who is ‘living better’ than almost anything else. ‘Don’t Die’ is a framework designed to counter that, uniting humanity and AI around a common goal” he explained.
At its core, Johnson’s message was a call to treat health not just as a personal ambition, but as a foundational algorithm for future civilization.
Read Part 2 of our round-up of Founders Longevity Forum London HERE.
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